Reaction Details Report a problem with these data
Target
Tissue alpha-L-fucosidase
Ligand
BDBM50133505
Substrate
n/a
Meas. Tech.
ChEMBL_33823 (CHEMBL646853)
IC50
1800±n/a nM
Citation
 Ogawa, S; Fujieda, S; Sakata, Y; Ishizaki, M; Hisamatsu, S; Okazaki, K Synthesis and glycosidase inhibitory activity of some N-substituted 6-deoxy-5a-carba-beta-DL- and L-galactopyranosylamines. Bioorg Med Chem Lett 13:3461-3 (2003) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50133505
Synonyms:
(1R,3R,6S)-4-Methyl-6-octylamino-cyclohexane-1,2,3-triol | CHEMBL117201
Type:
Small organic molecule
Emp. Form.:
C15H31NO3
Mol. Mass.:
273.4115
SMILES:
CCCCCCCCN[C@H]1CC(C)[C@@H](O)C(O)[C@@H]1O
Structure:
Search PDB for entries with ligand similarity: