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Target
DCN1-like protein 1
Ligand
BDBM50569309
Substrate
n/a
Meas. Tech.
ChEMBL_2108934 (CHEMBL4817609)
IC50
1948±n/a nM
Citation
 Zhou, W; Xu, C; Dong, G; Qiao, H; Yang, J; Liu, H; Ding, L; Sun, K; Zhao, W Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction. Eur J Med Chem 217:0 (2021) [PubMed]  Article 
Target
Name:
DCN1-like protein 1
Synonyms:
DCN1 | DCN1-like protein 1 | DCNL1_HUMAN | DCUN1 domain-containing protein 1 | DCUN1D1 | DCUN1L1 | Defective in cullin neddylation protein 1-like protein 1 | RP42 | SCCRO | Squamous cell carcinoma-related oncogene | Synonyms=DCN1
Type:
PROTEIN
Mol. Mass.:
30118.96
Organism:
Homo sapiens
Description:
ChEMBL_117443
Residue:
259
Sequence:
MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV
  
Inhibitor
Name:
BDBM50569309
Synonyms:
CHEMBL4855199
Type:
Small organic molecule
Emp. Form.:
C9H9N3OS
Mol. Mass.:
207.252
SMILES:
COc1ccccc1-c1nnc(S)[nH]1
Structure:
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