Reaction Details Report a problem with these data
Target
DCN1-like protein 5
Ligand
BDBM50569336
Substrate
n/a
Meas. Tech.
ChEMBL_2108941 (CHEMBL4817616)
Ki
>1000±n/a nM
Citation
 Zhou, W; Xu, C; Dong, G; Qiao, H; Yang, J; Liu, H; Ding, L; Sun, K; Zhao, W Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction. Eur J Med Chem 217:0 (2021) [PubMed]  Article 
Target
Name:
DCN1-like protein 5
Synonyms:
DCN1-like protein 5 | DCNL5 | DCNL5_HUMAN | DCUN1 domain-containing protein 5 | DCUN1D5 | Defective in cullin neddylation protein 1-like protein 5 | SCCRO5 | Squamous cell carcinoma-related oncogene 5 | Synonyms=SCCRO5
Type:
PROTEIN
Mol. Mass.:
27505.07
Organism:
Homo sapiens
Description:
ChEMBL_118182
Residue:
237
Sequence:
MPVKKKRKSPGVAAAVAEDGGLKKCKISSYCRSQPPARLISGEEHFSSKKCLAWFYEYAGPDEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQNKFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPVLLDEFVEWQKVRQTS
  
Inhibitor
Name:
BDBM50569336
Synonyms:
CHEMBL4865016
Type:
Small organic molecule
Emp. Form.:
C28H20N6S2
Mol. Mass.:
504.629
SMILES:
S(Sc1nnc([nH]1)-c1ccccc1-c1ccccc1)c1nnc([nH]1)-c1ccccc1-c1ccccc1
Structure:
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