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Target
Protein tyrosine phosphatase type IVA 2
Ligand
BDBM50059084
Substrate
n/a
Meas. Tech.
ChEMBL_2109207 (CHEMBL4817882)
IC50
130±n/a nM
Citation
 Lin, L; Lu, L; Yuan, C; Wang, A; Zhu, M; Fu, X; Xing, S The dual inhibition against the activity and expression of tyrosine phosphatase PRL-3 from a rhodanine derivative. Bioorg Med Chem Lett 41:0 (2021) [PubMed]  Article 
Target
Name:
Protein tyrosine phosphatase type IVA 2
Synonyms:
PRL2 | PTP4A2 | PTPCAAX2 | TP4A2_HUMAN
Type:
PROTEIN
Mol. Mass.:
19133.04
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461023
Residue:
167
Sequence:
MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ
  
Inhibitor
Name:
BDBM50059084
Synonyms:
CHEMBL3393171 | US10308663, Thienopyridone (5)
Type:
Small organic molecule
Emp. Form.:
C13H10N2OS
Mol. Mass.:
242.296
SMILES:
Nc1c[nH]c(=O)c2cc(sc12)-c1ccccc1
Structure:
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