Reaction Details Report a problem with these data
Target
Prostaglandin E2 receptor EP4 subtype
Ligand
BDBM50134518
Substrate
n/a
Meas. Tech.
ChEBML_158332
Ki
2000±n/a nM
Citation
 Gallant, M; Belley, M; Carrière, MC; Chateauneuf, A; Denis, D; Lachance, N; Lamontagne, S; Metters, KM; Sawyer, N; Slipetz, D; Truchon, JF; Labelle, M Structure-activity relationship of triaryl propionic acid analogues on the human EP3 prostanoid receptor. Bioorg Med Chem Lett 13:3813-6 (2003) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP4 subtype
Synonyms:
PE2R4_HUMAN | PGE receptor EP4 subtype | PGE2 receptor EP4 subtype | PTGER2 | PTGER4 | Prostaglandin E2 receptor | Prostanoid EP4 receptor
Type:
Enzyme
Mol. Mass.:
53134.53
Organism:
Homo sapiens (Human)
Description:
P35408
Residue:
488
Sequence:
MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
  
Inhibitor
Name:
BDBM50134518
Synonyms:
4-(2-Benzyloxy-[1,1';3',1'']terphenyl-2''-yl)-butyric acid | CHEMBL125269
Type:
Small organic molecule
Emp. Form.:
C29H26O3
Mol. Mass.:
422.5149
SMILES:
OC(=O)CCCc1ccccc1-c1cccc(c1)-c1ccccc1OCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: