Reaction Details Report a problem with these data
Target
P2Y purinoceptor 6
Ligand
BDBM50569572
Substrate
n/a
Meas. Tech.
ChEMBL_2109666 (CHEMBL4818341)
IC50
155±n/a nM
Citation
 Jung, YH; Jain, S; Gopinatth, V; Phung, NB; Gao, ZG; Jacobson, KA Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y Bioorg Med Chem Lett 41:0 (2021) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50569572
Synonyms:
CHEMBL4877204
Type:
Small organic molecule
Emp. Form.:
C19H18N6S4
Mol. Mass.:
458.646
SMILES:
S=C=Nc1ccc(NC(=S)NCCCNC(=S)Nc2ccc(cc2)N=C=S)cc1
Structure:
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