Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM50569861
Substrate
n/a
Meas. Tech.
ChEMBL_2110679 (CHEMBL4819529)
EC50
0.020000±n/a nM
Citation
 Xing, G; Woo, AY; Pan, L; Lin, B; Cheng, MS Recent Advances in ? J Med Chem 63:15218-15242 (2020) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50569861
Synonyms:
BI 1744 | CHEBI:82700 | Olodaterol | Striverdi respimat
Type:
Small organic molecule
Emp. Form.:
C21H26N2O5
Mol. Mass.:
386.4415
SMILES:
COc1ccc(CC(C)(C)NC[C@H](O)c2cc(O)cc3NC(=O)COc23)cc1 |r|
Structure:
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