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Target
Cathepsin G
Ligand
BDBM50135494
Substrate
n/a
Meas. Tech.
ChEBML_45349
IC50
>1000±n/a nM
Citation
 Masaki, H; Mizuno, Y; Tatui, A; Murakami, A; Koide, Y; Satoh, S; Takahashi, A Structure-activity relationship of benzo[b]thiophene-2-sulfonamide derivatives as novel human chymase inhibitors. Bioorg Med Chem Lett 13:4085-8 (2003) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50135494
Synonyms:
4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-3-methanesulfonyl-benzoic acid methyl ester | CHEMBL129901
Type:
Small organic molecule
Emp. Form.:
C18H16FNO6S3
Mol. Mass.:
457.516
SMILES:
COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(c1)S(C)(=O)=O
Structure:
Search PDB for entries with ligand similarity: