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Target
Interleukin-15
Ligand
BDBM50571044
Substrate
n/a
Meas. Tech.
ChEMBL_2113696 (CHEMBL4822546)
IC50
>30000±n/a nM
Citation
 Smadja, J; Quéméner, A; Maillasson, M; Sicard, B; Leray, A; Arzel, L; Lebreton, J; Mortier, E; Dubreuil, D; Mathé-Allainmat, M Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein. Bioorg Med Chem 39:0 (2021) [PubMed]  Article 
Target
Name:
Interleukin-15
Synonyms:
IL-15 | IL15_MOUSE | Il15 | Interleukin-15
Type:
PROTEIN
Mol. Mass.:
18588.73
Organism:
Mus musculus
Description:
ChEMBL_120403
Residue:
162
Sequence:
MKILKPYMRNTSISCYLCFLLNSHFLTEAGIHVFILGCVSVGLPKTEANWIDVRYDLEKIESLIQSIHIDTTLYTDSDFHPSCKVTAMNCFLLELQVILHEYSNMTLNETVRNVLYLANSTLSSNKNVAESGCKECEELEEKTFTEFLQSFIRIVQMFINTS
  
Inhibitor
Name:
BDBM50571044
Synonyms:
CHEMBL4878149
Type:
Small organic molecule
Emp. Form.:
C25H24Cl2N6O4S
Mol. Mass.:
575.467
SMILES:
Cn1c(Cc2nn(CCC3OCCO3)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl
Structure:
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