Reaction Details Report a problem with these data
Target
Interleukin-15
Ligand
BDBM50571051
Substrate
n/a
Meas. Tech.
ChEMBL_2113696 (CHEMBL4822546)
IC50
3500±n/a nM
Citation
 Smadja, J; Quéméner, A; Maillasson, M; Sicard, B; Leray, A; Arzel, L; Lebreton, J; Mortier, E; Dubreuil, D; Mathé-Allainmat, M Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein. Bioorg Med Chem 39:0 (2021) [PubMed]  Article 
Target
Name:
Interleukin-15
Synonyms:
IL-15 | IL15_MOUSE | Il15 | Interleukin-15
Type:
PROTEIN
Mol. Mass.:
18588.73
Organism:
Mus musculus
Description:
ChEMBL_120403
Residue:
162
Sequence:
MKILKPYMRNTSISCYLCFLLNSHFLTEAGIHVFILGCVSVGLPKTEANWIDVRYDLEKIESLIQSIHIDTTLYTDSDFHPSCKVTAMNCFLLELQVILHEYSNMTLNETVRNVLYLANSTLSSNKNVAESGCKECEELEEKTFTEFLQSFIRIVQMFINTS
  
Inhibitor
Name:
BDBM50571051
Synonyms:
CHEMBL4846844
Type:
Small organic molecule
Emp. Form.:
C26H28Cl2N6O2S
Mol. Mass.:
559.511
SMILES:
Cn1nc(Cc2nnc(SCCCCCCCC(=O)Nc3ccc(Cl)cc3Cl)[nH]2)c2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: