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Target
Interleukin-15
Ligand
BDBM50238648
Substrate
n/a
Meas. Tech.
ChEMBL_2113697 (CHEMBL4822547)
IC50
4500±n/a nM
Citation
 Smadja, J; Quéméner, A; Maillasson, M; Sicard, B; Leray, A; Arzel, L; Lebreton, J; Mortier, E; Dubreuil, D; Mathé-Allainmat, M Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 protein. Bioorg Med Chem 39:0 (2021) [PubMed]  Article 
Target
Name:
Interleukin-15
Synonyms:
IL-15 | IL15 | IL15-IL15 receptor | IL15_HUMAN | Interleukin-15
Type:
PROTEIN
Mol. Mass.:
18080.13
Organism:
Homo sapiens
Description:
ChEMBL_117698
Residue:
162
Sequence:
MRISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
  
Inhibitor
Name:
BDBM50238648
Synonyms:
CHEMBL4102828
Type:
Small organic molecule
Emp. Form.:
C21H18Cl2N6O2S
Mol. Mass.:
489.378
SMILES:
Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCC(=O)Nc1ccc(Cl)cc1Cl
Structure:
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