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Target
Rhomboid protease GlpG
Ligand
BDBM50572958
Substrate
n/a
Meas. Tech.
ChEMBL_2118695 (CHEMBL4827761)
IC50
2800±n/a nM
Citation
 Parsons, WH; Rutland, NT; Crainic, JA; Cardozo, JM; Chow, AS; Andrews, CL; Sheehan, BK Development of succinimide-based inhibitors for the mitochondrial rhomboid protease PARL. Bioorg Med Chem Lett 49:0 (2021) [PubMed]  Article 
Target
Name:
Rhomboid protease GlpG
Synonyms:
GLPG_ECOLI | Rhomboid protease (EcGlpG) | glpG
Type:
Protein
Mol. Mass.:
31313.89
Organism:
Escherichia coli (Enterobacteria)
Description:
P09391
Residue:
276
Sequence:
MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
  
Inhibitor
Name:
BDBM50572958
Synonyms:
CHEMBL4856971
Type:
Small organic molecule
Emp. Form.:
C15H10ClNO5S
Mol. Mass.:
351.762
SMILES:
Clc1ccccc1C(=O)OCN1C(=O)c2ccccc2S1(=O)=O
Structure:
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