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Target
D(3) dopamine receptor
Ligand
BDBM50573371
Substrate
n/a
Meas. Tech.
ChEMBL_2119480 (CHEMBL4828546)
Ki
50±n/a nM
Citation
 Shaik, AB; Boateng, CA; Battiti, FO; Bonifazi, A; Cao, J; Chen, L; Chitsazi, R; Ravi, S; Lee, KH; Shi, L; Newman, AH Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D J Med Chem 64:15313-15333 (2021) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_HUMAN | Dopamine D3 receptor
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Homo sapiens
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50573371
Synonyms:
CHEMBL4876353
Type:
Small organic molecule
Emp. Form.:
C26H35ClN4O4
Mol. Mass.:
503.033
SMILES:
CCc1cc(Cl)c(OC)c(C(=O)NC[C@@H]2CCCN2CCc2c(C)nc3CCCCn3c2=O)c1O |r|
Structure:
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