Reaction Details Report a problem with these data
Target
Tyrosinase
Ligand
BDBM50139367
Substrate
n/a
Meas. Tech.
ChEBML_210707
IC50
3300000±n/a nM
Citation
 Nihei, K; Yamagiwa, Y; Kamikawa, T; Kubo, I 2-hydroxy-4-isopropylbenzaldehyde, a potent partial tyrosinase inhibitor. Bioorg Med Chem Lett 14:681-3 (2004) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB
Type:
Protein
Mol. Mass.:
60388.08
Organism:
Homo sapiens (Human)
Description:
P14679
Residue:
529
Sequence:
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLGAAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
  
Inhibitor
Name:
BDBM50139367
Synonyms:
2-hydroxybenzaldehyde | CHEMBL108925 | Salicylaldehyd | Salizylaldehyd | o-formylphenol | salicylal | salicylaldehyde
Type:
Small organic molecule
Emp. Form.:
C7H6O2
Mol. Mass.:
122.1213
SMILES:
Oc1ccccc1C=O
Structure:
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