Target
Adenosine receptor A2b
Ligand
BDBM50573588
Substrate
n/a
Meas. Tech.
ChEMBL_2119774 (CHEMBL4828921)
Ki
1380±n/a nM
Citation
 Bednarska-Szczepaniak, KMieczkowski, AKierozalska, APavlovi? Safti?, DG??ba?a, KPrzygodzki, TSta?czyk, LKarolczak, KWata?a, CRao, HGao, ZGJacobson, KALe?nikowski, ZJ Synthesis and evaluation of adenosine derivatives as A Eur J Med Chem 223:0 (2021) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50573588
Synonyms:
CHEMBL4871554
Type:
Small organic molecule
Emp. Form.:
C21H26N6O4
Mol. Mass.:
426.4689
SMILES:
CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCCCc3ccccc3)ncnc12 |r|
Structure:
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