Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM50142227
Substrate
n/a
Meas. Tech.
ChEBML_105277
Ki
4.8±n/a nM
Citation
 Epperson, JR; Deskus, JA; Gentile, AJ; Iben, LG; Ryan, E; Sarbin, NS 4-Substituted anilides as selective melatonin MT2 receptor agonists. Bioorg Med Chem Lett 14:1023-6 (2004) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50142227
Synonyms:
CHEMBL7567 | Cyclopropanecarboxylic acid {4-[(3-methoxy-phenyl)-methyl-amino]-phenyl}-amide
Type:
Small organic molecule
Emp. Form.:
C18H20N2O2
Mol. Mass.:
296.3636
SMILES:
COc1cccc(c1)N(C)c1ccc(NC(=O)C2CC2)cc1
Structure:
Search PDB for entries with ligand similarity: