Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50117223
Substrate
n/a
Meas. Tech.
ChEMBL_31841 (CHEMBL641518)
Ki
0.180000±n/a nM
Citation
 Okamura, T; Kurogi, Y; Hashimoto, K; Nishikawa, H; Nagao, Y Facile synthesis of fused 1,2,4-triazolo[1,5-c]pyrimidine derivatives as human adenosine A3 receptor ligands. Bioorg Med Chem Lett 14:2443-6 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50117223
Synonyms:
5-Butyl-8-(4-methoxy-phenyl)-3H-[1,2,4]triazolo[5,1-i]purine | CHEMBL331111
Type:
Small organic molecule
Emp. Form.:
C17H18N6O
Mol. Mass.:
322.3644
SMILES:
CCCCc1nc2nc[nH]c2c2nc(nn12)-c1ccc(OC)cc1
Structure:
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