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Target
Adenosine receptor A1
Ligand
BDBM50090704
Substrate
n/a
Meas. Tech.
ChEMBL_29102 (CHEMBL638714)
Ki
39±n/a nM
Citation
 Ferrarini, PL; Betti, L; Cavallini, T; Giannaccini, G; Lucacchini, A; Manera, C; Martinelli, A; Ortore, G; Saccomanni, G; Tuccinardi, T Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives. J Med Chem 47:3019-31 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50090704
Synonyms:
CHEMBL97624 | Cyclohexyl-(7-methyl-2-phenyl-[1,8]naphthyridin-4-yl)-amine | N-cyclohexyl-7-methyl-2-phenyl-1,8-naphthyridin-4-amine
Type:
Small organic molecule
Emp. Form.:
C21H23N3
Mol. Mass.:
317.4274
SMILES:
Cc1ccc2c(NC3CCCCC3)cc(nc2n1)-c1ccccc1
Structure:
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