Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50580163
Substrate
n/a
Meas. Tech.
ChEMBL_2147329 (CHEMBL5031675)
Ki
2.4±n/a nM
Citation
 Lee, Y; Hou, X; Lee, JH; Nayak, A; Alexander, V; Sharma, PK; Chang, H; Phan, K; Gao, ZG; Jacobson, KA; Choi, S; Jeong, LS Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A J Med Chem 64:12525-12536 (2021) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50580163
Synonyms:
CHEMBL5075606
Type:
Small organic molecule
Emp. Form.:
C10H14N6OS
Mol. Mass.:
266.323
SMILES:
CNc1ncnc2n(cnc12)[C@@H]1SC[C@@H](N)[C@H]1O |r|
Structure:
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