Reaction Details Report a problem with these data
Target
Glutathione S-transferase P
Ligand
BDBM50148144
Substrate
n/a
Meas. Tech.
ChEMBL_72453 (CHEMBL686008)
Ki
6100±n/a nM
Citation
 Wu, Z; Minhas, GS; Wen, D; Jiang, H; Chen, K; Zimniak, P; Zheng, J Design, synthesis, and structure-activity relationships of haloenol lactones: site-directed and isozyme-selective glutathione S-transferase inhibitors. J Med Chem 47:3282-94 (2004) [PubMed]  Article 
Target
Name:
Glutathione S-transferase P
Synonyms:
FAEES3 | GST class-pi | GST3 | GSTP1 | GSTP1-1 | GSTP1_HUMAN | Glutathione S-transferase | Glutathione S-transferase (GST) | Glutathione S-transferase P | Glutathione S-transferase Pi | Glutathione transferase (GST)
Type:
Enzyme
Mol. Mass.:
23353.53
Organism:
Homo sapiens (Human)
Description:
P09211
Residue:
210
Sequence:
MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
  
Inhibitor
Name:
BDBM50148144
Synonyms:
5-[1-Bromo-meth-(E)-ylidene]-3-((E)-styryl)-dihydro-furan-2-one | CHEMBL109304
Type:
Small organic molecule
Emp. Form.:
C14H13BrO2
Mol. Mass.:
293.156
SMILES:
Br\C=C1/CC(C\C=C\c2ccccc2)C(=O)O1
Structure:
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