Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 1
Ligand
BDBM50148355
Substrate
n/a
Meas. Tech.
ChEBML_100173
EC50
1950±n/a nM
Citation
 Santos, WL; Heasley, BH; Jarosz, R; Carter, KM; Lynch, KR; Macdonald, TL Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid. Bioorg Med Chem Lett 14:3473-6 (2004) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 1
Synonyms:
EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2
Type:
Enzyme
Mol. Mass.:
41120.55
Organism:
Homo sapiens (Human)
Description:
Q92633
Residue:
364
Sequence:
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
  
Inhibitor
Name:
BDBM50148355
Synonyms:
CHEMBL331661 | [3-((Z)-Octadec-9-enoylamino)-propyl]-phosphonic acid
Type:
Small organic molecule
Emp. Form.:
C21H42NO4P
Mol. Mass.:
403.5362
SMILES:
CCCCCCCC\C=C/CCCCCCCC(=O)NCCCP(O)(O)=O
Structure:
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