Reaction Details
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Report a problem with these dataTarget
Lysophosphatidic acid receptor 2
Ligand
BDBM50148435
Substrate
n/a
Meas. Tech.
ChEBML_201449
IC50
6.6±n/a nM
Citation
Hale, JJ; Doherty, G; Toth, L; Mills, SG; Hajdu, R; Keohane, CA; Rosenbach, M; Milligan, J; Shei, GJ; Chrebet, G; Bergstrom, J; Card, D; Forrest, M; Sun, SY; West, S; Xie, H; Nomura, N; Rosen, H; Mandala, S Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists. Bioorg Med Chem Lett 14:3501-5 (2004) [PubMed] Article More Info.:
Target
Name:
Lysophosphatidic acid receptor 2
Synonyms:
EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4
Type:
PROTEIN
Mol. Mass.:
39103.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1451385
Residue:
351
Sequence:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
Inhibitor
Name:
BDBM50148435
Synonyms:
CHEMBL119116 | [3-(3,5-Dichloro-4-octyloxy-benzylamino)-propyl]-phosphonic acid
Type:
Small organic molecule
Emp. Form.:
C18H30Cl2NO4P
Mol. Mass.:
426.315
SMILES:
CCCCCCCCOc1c(Cl)cc(CNCCCP(O)(O)=O)cc1Cl
Structure:
