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Target
Programmed cell death 1 ligand 1
Ligand
BDBM50580530
Substrate
n/a
Meas. Tech.
ChEMBL_2148562 (CHEMBL5032960)
Kd
3.3±n/a nM
Citation
 Liu, L; Yao, Z; Wang, S; Xie, T; Wu, G; Zhang, H; Zhang, P; Wu, Y; Yuan, H; Sun, H Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[ J Med Chem 64:8391-8409 (2021) [PubMed]  Article 
Target
Name:
Programmed cell death 1 ligand 1
Synonyms:
B7 homolog 1 | B7-H1 | B7H1 | B7H1 | CD274 | CD_antigen=CD274 | PD-L1 | PD1L1_HUMAN | PDCD1 ligand 1 | PDCD1L1 | PDCD1LG1 | PDL1 | Programmed cell death 1 ligand 1 | Programmed death ligand 1
Type:
PROTEIN
Mol. Mass.:
33278.49
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109807
Residue:
290
Sequence:
MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
  
Inhibitor
Name:
BDBM50580530
Synonyms:
CHEMBL5092744
Type:
Small organic molecule
Emp. Form.:
C30H25BrClN3O6
Mol. Mass.:
638.893
SMILES:
OC[C@@H](NCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCc1ccc2nonc2c1)C(O)=O |r|
Structure:
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