Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM50149787
Substrate
n/a
Meas. Tech.
ChEMBL_302784 (CHEMBL839469)
Ki
1000±n/a nM
Citation
 Buzzoni, V; Blazquez, J; Ferrari, S; Calò, S; Venturelli, A; Costi, MP Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase. Bioorg Med Chem Lett 14:3979-83 (2004) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM50149787
Synonyms:
Aza-boronic acid derivative | CHEMBL366099
Type:
Small organic molecule
Emp. Form.:
C11H12BN3O3
Mol. Mass.:
245.042
SMILES:
Cc1noc(C)c1\N=N\c1cccc(c1)B(O)O
Structure:
Search PDB for entries with ligand similarity: