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Target
Adenosine kinase
Ligand
BDBM50150300
Substrate
n/a
Meas. Tech.
ChEMBL_305608 (CHEMBL828146)
IC50
120±n/a nM
Citation
 Gomtsyan, A; Didomenico, S; Lee, CH; Stewart, AO; Bhagwat, SS; Kowaluk, EA; Jarvis, MF Synthesis and biological evaluation of pteridine and pyrazolopyrimidine based adenosine kinase inhibitors. Bioorg Med Chem Lett 14:4165-8 (2004) [PubMed]  Article 
Target
Name:
Adenosine kinase
Synonyms:
ADK | ADK_HUMAN
Type:
PROTEIN
Mol. Mass.:
40545.97
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1467841
Residue:
362
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH
  
Inhibitor
Name:
BDBM50150300
Synonyms:
CHEMBL359631 | [7-(6-Morpholin-4-yl-pyridin-3-yl)-pteridin-4-yl]-phenethyl-amine
Type:
Small organic molecule
Emp. Form.:
C23H23N7O
Mol. Mass.:
413.475
SMILES:
C(Cc1ccccc1)Nc1ncnc2nc(cnc12)-c1ccc(nc1)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: