Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50150410
Substrate
n/a
Meas. Tech.
ChEMBL_302565 (CHEMBL839527)
Ki
>1000±n/a nM
Citation
 Mattson, RJ; Denhart, DJ; Catt, JD; Dee, MF; Deskus, JA; Ditta, JL; Epperson, J; Dalton King, H; Gao, A; Poss, MA; Purandare, A; Tortolani, D; Zhao, Y; Yang, H; Yeola, S; Palmer, J; Torrente, J; Stark, A; Johnson, G Aminotriazine 5-HT7 antagonists. Bioorg Med Chem Lett 14:4245-8 (2004) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
51836.79
Organism:
Homo sapiens (Human)
Description:
P28335
Residue:
458
Sequence:
MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
  
Inhibitor
Name:
BDBM50150410
Synonyms:
CHEMBL182174 | N-(2-Phenoxy-ethyl)-N''-((S)-1-phenyl-ethyl)-[1,3,5]triazine-2,4,6-triamine
Type:
Small organic molecule
Emp. Form.:
C19H22N6O
Mol. Mass.:
350.4176
SMILES:
C[C@H](Nc1nc(N)nc(NCCOc2ccccc2)n1)c1ccccc1
Structure:
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