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Target
M-phase inducer phosphatase 1
Ligand
BDBM50150612
Substrate
n/a
Meas. Tech.
ChEMBL_305898 (CHEMBL832081)
IC50
24500±n/a nM
Citation
 Shimazawa, R; Gochomori, M; Shirai, R Design and synthesis of novel Cdc25A-inhibitors having phosphate group as a hydrophilic residue. Bioorg Med Chem Lett 14:4339-42 (2004) [PubMed]  Article 
Target
Name:
M-phase inducer phosphatase 1
Synonyms:
CDC25A | Dual specificity phosphatase (Cdc25A) | Dual specificity phosphatase Cdc25A | M-phase inducer phosphatase 1 | MPIP1_HUMAN | phosphatase Cdc25
Type:
Protein
Mol. Mass.:
59090.18
Organism:
Homo sapiens (Human)
Description:
P30304
Residue:
524
Sequence:
MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
  
Inhibitor
Name:
BDBM50150612
Synonyms:
CHEMBL181402 | CHEMBL182548 | Phosphoric acid mono-{2-[1-(1,5-dimethyl-hexyl)-4,7a-dimethyl-octahydro-inden-4-yl]-ethyl} ester
Type:
Small organic molecule
Emp. Form.:
C21H41O4P
Mol. Mass.:
388.5216
SMILES:
CC(C)CCC[C@@H](C)[C@H]1CCC2[C@]1(C)CCCC2(C)CCOP(O)(O)=O
Structure:
Search PDB for entries with ligand similarity: