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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50150837
Substrate
n/a
Meas. Tech.
ChEMBL_302491 (CHEMBL827181)
Ki
360±n/a nM
Citation
 Chen, C; Yu, J; Fleck, BA; Hoare, SR; Saunders, J; Foster, AC Phenylguanidines as selective nonpeptide melanocortin-5 receptor antagonists. J Med Chem 47:4083-8 (2004) [PubMed]  Article 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM50150837
Synonyms:
4-[((S)-N-(R)-Cyclohexyl-2,5-dimethyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide | CHEMBL184432
Type:
Small organic molecule
Emp. Form.:
C28H37Cl2N5O
Mol. Mass.:
530.532
SMILES:
C[C@H]1CN([C@H](C)CN1)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1 |w:29.32|
Structure:
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