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Target
Melanocortin receptor 5
Ligand
BDBM50150843
Substrate
n/a
Meas. Tech.
ChEMBL_303300 (CHEMBL827433)
Ki
360±n/a nM
Citation
 Chen, C; Yu, J; Fleck, BA; Hoare, SR; Saunders, J; Foster, AC Phenylguanidines as selective nonpeptide melanocortin-5 receptor antagonists. J Med Chem 47:4083-8 (2004) [PubMed]  Article 
Target
Name:
Melanocortin receptor 5
Synonyms:
MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36612.92
Organism:
Homo sapiens (Human)
Description:
P33032
Residue:
325
Sequence:
MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
  
Inhibitor
Name:
BDBM50150843
Synonyms:
4-(N''''-Cyclohexyl-N'',N''-dipropyl-guanidino)-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide | CHEMBL186189
Type:
Small organic molecule
Emp. Form.:
C28H38Cl2N4O
Mol. Mass.:
517.534
SMILES:
CCCN(CCC)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1 |w:28.30|
Structure:
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