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Target
Melanocortin receptor 4
Ligand
BDBM50150831
Substrate
n/a
Meas. Tech.
ChEMBL_302493 (CHEMBL828210)
Ki
1400±n/a nM
Citation
 Chen, C; Yu, J; Fleck, BA; Hoare, SR; Saunders, J; Foster, AC Phenylguanidines as selective nonpeptide melanocortin-5 receptor antagonists. J Med Chem 47:4083-8 (2004) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM50150831
Synonyms:
4-[(N-Cyclohexyl-3-methylamino-pyrrolidine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide | CHEMBL186439
Type:
Small organic molecule
Emp. Form.:
C27H35Cl2N5O
Mol. Mass.:
516.506
SMILES:
CNC1CCN(C1)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1 |w:28.31|
Structure:
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