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Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50458526
Substrate
n/a
Meas. Tech.
ChEMBL_2155112 (CHEMBL5039772)
EC50
21±n/a nM
Citation
 Lee, J; Kwag, R; Lee, S; Kim, D; Woo, J; Cho, Y; Kim, HJ; Kim, J; Jeon, B; Choo, H Discovery of G Protein-Biased Ligands against 5-HT J Med Chem 64:7453-7467 (2021) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50458526
Synonyms:
CHEMBL4205349
Type:
Small organic molecule
Emp. Form.:
C16H23N3
Mol. Mass.:
257.3739
SMILES:
CN(C)CCc1cccc(c1)-c1c(C)nn(C)c1C
Structure:
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