Reaction Details Report a problem with these data
Target
Alpha-synuclein
Ligand
BDBM50582844
Substrate
n/a
Meas. Tech.
ChEMBL_2155874 (CHEMBL5040534)
Kd
380±n/a nM
Citation
 Bian, J; Liu, YQ; He, J; Lin, X; Qiu, CY; Yu, WB; Shen, Y; Zhu, ZY; Ye, DY; Wang, J; Chu, Y Discovery of styrylaniline derivatives as novel alpha-synuclein aggregates ligands. Eur J Med Chem 226:0 (2021) [PubMed]  Article 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM50582844
Synonyms:
CHEMBL5084363
Type:
Small organic molecule
Emp. Form.:
C21H16N2O3
Mol. Mass.:
344.3633
SMILES:
[O-][N+](=O)c1cccc(\C=C\c2ccccc2NC(=O)c2ccccc2)c1
Structure:
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