Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50152221
Substrate
n/a
Meas. Tech.
ChEMBL_303558 (CHEMBL828958)
Ki
>250±n/a nM
Citation
 Vu, CB; Pan, D; Peng, B; Sha, L; Kumaravel, G; Jin, X; Phadke, D; Engber, T; Huang, C; Reilly, J; Tam, S; Petter, RC Studies on adenosine A2a receptor antagonists: comparison of three core heterocycles. Bioorg Med Chem Lett 14:4831-4 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50152221
Synonyms:
2-Furan-2-yl-N*7*-[(R)-1-(5-methyl-isoxazol-3-ylmethyl)-pyrrolidin-2-ylmethyl]-[1,2,4]triazolo[1,5-c]pyrimidine-5,7-diamine | CHEMBL184002
Type:
Small organic molecule
Emp. Form.:
C19H22N8O2
Mol. Mass.:
394.4304
SMILES:
Cc1cc(CN2CCC[C@@H]2CNc2cc3nc(nn3c(N)n2)-c2ccco2)no1
Structure:
Search PDB for entries with ligand similarity: