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Target
Prostaglandin D2 receptor
Ligand
BDBM50152508
Substrate
n/a
Meas. Tech.
ChEMBL_303622 (CHEMBL828877)
Ki
10±n/a nM
Citation
 Torisu, K; Kobayashi, K; Iwahashi, M; Nakai, Y; Onoda, T; Nagase, T; Sugimoto, I; Okada, Y; Matsumoto, R; Nanbu, F; Ohuchida, S; Nakai, H; Toda, M Discovery of orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett 14:4891-5 (2004) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50152508
Synonyms:
CHEMBL364593 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid
Type:
Small organic molecule
Emp. Form.:
C27H23NO6
Mol. Mass.:
457.4746
SMILES:
Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OC[C@@H]2COc3ccccc3O2)cc1
Structure:
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