Reaction Details
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Adenosine receptor A2b
Ligand
BDBM50397728
Substrate
n/a
Meas. Tech.
ChEMBL_2157705 (CHEMBL5042365)
Ki
189±n/a nM
Citation
Suresh, RR; Gao, ZG; Salmaso, V; Chen, E; Campbell, RG; Poe, RB; Liston, TE; Jacobson, KA Selective A ACS Med Chem Lett 13:623-631 (2022) [PubMed] Article More Info.:
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_MOUSE | Adenosine A2b receptor | Adora2b
Type:
PROTEIN
Mol. Mass.:
36130.09
Organism:
Mus musculus
Description:
ChEMBL_11831
Residue:
332
Sequence:
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHGCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDSATSNCTELGDGIANKSCCPVTCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFMVACKQLQRMELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHKIISRYVLCQAETKGGSGQAGAQSTLSLGL
Inhibitor
Name:
BDBM50397728
Synonyms:
CHEMBL2181976
Type:
Small organic molecule
Emp. Form.:
C22H18N4OS
Mol. Mass.:
386.47
SMILES:
Cc1cc(C)cc(c1)-c1nc(NC(=O)c2cccnc2)sc1-c1ccncc1
Structure:
