Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50583543
Substrate
n/a
Meas. Tech.
ChEMBL_2157718 (CHEMBL5042378)
Ki
252±n/a nM
Citation
 Suresh, RR; Gao, ZG; Salmaso, V; Chen, E; Campbell, RG; Poe, RB; Liston, TE; Jacobson, KA Selective A ACS Med Chem Lett 13:623-631 (2022) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_MOUSE | Adenosine A1 receptor | Adenosine receptor A1 | Adora1
Type:
PROTEIN
Mol. Mass.:
36646.06
Organism:
Mus musculus
Description:
ChEMBL_479902
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSEVEQAWIANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIEEDIPEEKADD
  
Inhibitor
Name:
BDBM50583543
Synonyms:
CHEMBL5081520
Type:
Small organic molecule
Emp. Form.:
C21H15BrN4OS
Mol. Mass.:
451.339
SMILES:
Cc1cc(Br)cc(c1)-c1nc(NC(=O)c2cccnc2)sc1-c1ccncc1
Structure:
Search PDB for entries with ligand similarity: