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Target
Fatty acid-binding protein, intestinal
Ligand
BDBM50152857
Substrate
n/a
Meas. Tech.
ChEMBL_305929 (CHEMBL833476)
IC50
42000±n/a nM
Citation
 Lehmann, F; Haile, S; Axen, E; Medina, C; Uppenberg, J; Svensson, S; Lundbäck, T; Rondahl, L; Barf, T Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg Med Chem Lett 14:4445-8 (2004) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, intestinal
Synonyms:
FABP2 | FABPI | FABPI_HUMAN | Fatty acid binding protein intestinal | Fatty acid-binding protein, intestinal | I-FABP | Intestinal fatty acid-binding protein (hIFABP)
Type:
Protein
Mol. Mass.:
15207.56
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
132
Sequence:
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD
  
Inhibitor
Name:
BDBM50152857
Synonyms:
3-(Carbazole-9-sulfonyl)-thiophene-2-carboxylic acid | CHEMBL363032
Type:
Small organic molecule
Emp. Form.:
C17H11NO4S2
Mol. Mass.:
357.404
SMILES:
OC(=O)c1sccc1S(=O)(=O)n1c2ccccc2c2ccccc12
Structure:
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