Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 2
Ligand
BDBM50583777
Substrate
n/a
Meas. Tech.
ChEMBL_2158117 (CHEMBL5042867)
Ki
4300±n/a nM
Citation
 Quillet, R; Schneider, S; Utard, V; Drieu la Rochelle, A; Elhabazi, K; Henningsen, JB; Gizzi, P; Schmitt, M; Kugler, V; Simonneaux, V; Ilien, B; Simonin, F; Bihel, F Identification of an  J Med Chem 64:7555-7564 (2021) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 2
Synonyms:
G-protein coupled receptor 74 | Gpr74 | NPFF2_MOUSE | Neuropeptide NPFF receptor | Npff2 | Npffr2
Type:
PROTEIN
Mol. Mass.:
47466.10
Organism:
Mus musculus
Description:
ChEMBL_119166
Residue:
417
Sequence:
MSEKWDSNSSESWNHIWSGNDTQHHWYSDINITYVNYYLHQPQVAAVFISSYLLIFVLCMVGNTVVCFIVIRNRHMHTVTNFFILNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVTIVIIWGLAIAIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPRHEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTAAHCTGKQRPVQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYTDLSPNKLRIINIYIYPFAHWLAFCNSSVNPIIYGFFNENFRNGFQDAFQICQKKAKPQEAYSLRAKRNIVINTSGLLVQEPVSQNPGGENLGCGKSADNPTQESLIEEMGEATNSTVA
  
Inhibitor
Name:
BDBM50583777
Synonyms:
CHEMBL5085324
Type:
Small organic molecule
Emp. Form.:
C27H36N6O3
Mol. Mass.:
492.6131
SMILES:
[#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]-[#7]-[#6](-[#7])=[#7])-[#7]-[#6](=O)\[#6]=[#6](\c1ccccc1)-c1ccccc1)-[#6](-[#7])=O |r|
Structure:
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