Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 2
Ligand
BDBM50565180
Substrate
n/a
Meas. Tech.
ChEMBL_2158117 (CHEMBL5042867)
Ki
824±n/a nM
Citation
 Quillet, R; Schneider, S; Utard, V; Drieu la Rochelle, A; Elhabazi, K; Henningsen, JB; Gizzi, P; Schmitt, M; Kugler, V; Simonneaux, V; Ilien, B; Simonin, F; Bihel, F Identification of an  J Med Chem 64:7555-7564 (2021) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 2
Synonyms:
G-protein coupled receptor 74 | Gpr74 | NPFF2_MOUSE | Neuropeptide NPFF receptor | Npff2 | Npffr2
Type:
PROTEIN
Mol. Mass.:
47466.10
Organism:
Mus musculus
Description:
ChEMBL_119166
Residue:
417
Sequence:
MSEKWDSNSSESWNHIWSGNDTQHHWYSDINITYVNYYLHQPQVAAVFISSYLLIFVLCMVGNTVVCFIVIRNRHMHTVTNFFILNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVTIVIIWGLAIAIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPRHEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTAAHCTGKQRPVQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYTDLSPNKLRIINIYIYPFAHWLAFCNSSVNPIIYGFFNENFRNGFQDAFQICQKKAKPQEAYSLRAKRNIVINTSGLLVQEPVSQNPGGENLGCGKSADNPTQESLIEEMGEATNSTVA
  
Inhibitor
Name:
BDBM50565180
Synonyms:
CHEMBL4776204
Type:
Small organic molecule
Emp. Form.:
C28H32N6O3
Mol. Mass.:
500.5921
SMILES:
NC(=N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C(N)=O)c1ccccc1 |r|
Structure:
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