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Target
Vasopressin V2 receptor
Ligand
BDBM50152978
Substrate
n/a
Meas. Tech.
ChEMBL_304151 (CHEMBL828131)
EC50
1300±n/a nM
Citation
 Pitt, GR; Batt, AR; Haigh, RM; Penson, AM; Robson, PA; Rooker, DP; Tartar, AL; Trim, JE; Yea, CM; Roe, MB Non-peptide oxytocin agonists. Bioorg Med Chem Lett 14:4585-9 (2004) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
ADHR | AVPR V2 | AVPR2 | Antidiuretic hormone receptor | DIR | DIR3 | Renal-type arginine vasopressin receptor | V2R | V2R_HUMAN | VASOPRESSIN V2 | Vasopressin V2 receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
40295.28
Organism:
Homo sapiens (Human)
Description:
P30518
Residue:
371
Sequence:
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS
  
Inhibitor
Name:
BDBM50152978
Synonyms:
(3S,5R)-4-Methoxy-2-(4-methyl-[1,4]diazepane-1-carbonyl)-pyrrolidine-1-carboxylic acid 2-chloro-4-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-benzylamide | CHEMBL364994
Type:
Small organic molecule
Emp. Form.:
C29H38ClN5O4S
Mol. Mass.:
588.161
SMILES:
CO[C@@H]1C[C@H](N(C1)C(=O)NCc1ccc(cc1Cl)C(=O)N1CCCCc2sccc12)C(=O)N1CCCN(C)CC1
Structure:
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