Reaction Details Report a problem with these data
Target
Peptide deformylase
Ligand
BDBM50153079
Substrate
n/a
Meas. Tech.
ChEMBL_303553 (CHEMBL828953)
Ki
258±n/a nM
Citation
 Hu, X; Nguyen, KT; Jiang, VC; Lofland, D; Moser, HE; Pei, D Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size. J Med Chem 47:4941-9 (2004) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2
Type:
n/a
Mol. Mass.:
16901.39
Organism:
Escherichia coli
Description:
n/a
Residue:
150
Sequence:
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIGLRLGNGKYCTLRLFFNQV
  
Inhibitor
Name:
BDBM50153079
Synonyms:
CHEMBL364979 | N-[(3S,6R)-3-(4-Amino-butyl)-2,5-dioxo-1,4diaza-cycloicos-6-ylmethyl]-N-hydroxy-formamide
Type:
Small organic molecule
Emp. Form.:
C24H46N4O4
Mol. Mass.:
454.6464
SMILES:
NCCCC[C@@H]1NC(=O)[C@@H](CN(O)C=O)CCCCCCCCCCCCCCNC1=O
Structure:
Search PDB for entries with ligand similarity: