Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50153258
Substrate
n/a
Meas. Tech.
ChEMBL_310597 (CHEMBL834253)
EC50
>10000±n/a nM
Citation
 Matulenko, MA; Surber, B; Fan, L; Kolasa, T; Nakane, M; Terranova, MA; Uchic, ME; Miller, LN; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Moreland, RB; Brioni, JD; Stewart, AO Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand. Bioorg Med Chem Lett 14:5095-8 (2004) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50153258
Synonyms:
2-(4-Biphenyl-4-yl-piperazin-1-yl)-N-m-tolyl-acetamide | CHEMBL184263
Type:
Small organic molecule
Emp. Form.:
C25H27N3O
Mol. Mass.:
385.5014
SMILES:
Cc1cccc(NC(=O)CN2CCN(CC2)c2ccc(cc2)-c2ccccc2)c1
Structure:
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