Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50153262
Substrate
n/a
Meas. Tech.
ChEMBL_302872 (CHEMBL828786)
Ki
>10000±n/a nM
Citation
 Matulenko, MA; Surber, B; Fan, L; Kolasa, T; Nakane, M; Terranova, MA; Uchic, ME; Miller, LN; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Moreland, RB; Brioni, JD; Stewart, AO Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand. Bioorg Med Chem Lett 14:5095-8 (2004) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50153262
Synonyms:
2-(4-Pyridin-4-yl-piperazin-1-yl)-N-m-tolyl-acetamide | CHEMBL364865
Type:
Small organic molecule
Emp. Form.:
C18H22N4O
Mol. Mass.:
310.3935
SMILES:
Cc1cccc(NC(=O)CN2CCN(CC2)c2ccncc2)c1
Structure:
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