Reaction Details Report a problem with these data
Target
Putative cathepsin L 3
Ligand
BDBM50153289
Substrate
n/a
Meas. Tech.
ChEMBL_305344 (CHEMBL832724)
IC50
250000±n/a nM
Citation
 Chircorian, A; Barrios, AM Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I). Bioorg Med Chem Lett 14:5113-6 (2004) [PubMed]  Article 
Target
Name:
Putative cathepsin L 3
Synonyms:
CATL3_PARTE | Cathepsin L2
Type:
PROTEIN
Mol. Mass.:
35182.45
Organism:
Paramecium tetraurelia
Description:
ChEMBL_302746
Residue:
308
Sequence:
MKQFLTAAIVTLLMTAGYYHLQEDDTNDFERWALKNNKFYTESEKLYRMEIYNSNKRMIEEHNQREDVTYQMGENQFMTLSHEEFVDLYLQKSDSSVNIMGASLPEVQLEGLGAVDWRNYTTVKEQGQCASGWAFSVSNSLEAWYAIRGFQKINASTQQIVDCDYNNTGCSGGYNAYAMEYVLRVGLVSSTNYPYVAKNQTCKQSRNGTYFINGYSFVGGSQSNLQYYLNNYPISVGVEASNWQFYRSGLFSNCSSNGTNHYALAVGFDSANNWIVQNSWGTQWGESGNIRLYPQNTCGILNYPYQVY
  
Inhibitor
Name:
BDBM50153289
Synonyms:
CHEMBL182346 | disodium [2-(sulfanyl-kappaS)butanedioato(3-)]aurate(2-) | disodium aurothiomalate
Type:
Small organic molecule
Emp. Form.:
C4H3AuO4S
Mol. Mass.:
344.097
SMILES:
[O-]C(=O)CC(S[Au])C([O-])=O
Structure:
Search PDB for entries with ligand similarity: