Reaction Details Report a problem with these data
Target
Putative cathepsin L 3
Ligand
BDBM50153291
Substrate
n/a
Meas. Tech.
ChEMBL_302746 (CHEMBL852353)
Ki
500000±n/a nM
Citation
 Chircorian, A; Barrios, AM Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I). Bioorg Med Chem Lett 14:5113-6 (2004) [PubMed]  Article 
Target
Name:
Putative cathepsin L 3
Synonyms:
CATL3_PARTE | Cathepsin L2
Type:
PROTEIN
Mol. Mass.:
35182.45
Organism:
Paramecium tetraurelia
Description:
ChEMBL_302746
Residue:
308
Sequence:
MKQFLTAAIVTLLMTAGYYHLQEDDTNDFERWALKNNKFYTESEKLYRMEIYNSNKRMIEEHNQREDVTYQMGENQFMTLSHEEFVDLYLQKSDSSVNIMGASLPEVQLEGLGAVDWRNYTTVKEQGQCASGWAFSVSNSLEAWYAIRGFQKINASTQQIVDCDYNNTGCSGGYNAYAMEYVLRVGLVSSTNYPYVAKNQTCKQSRNGTYFINGYSFVGGSQSNLQYYLNNYPISVGVEASNWQFYRSGLFSNCSSNGTNHYALAVGFDSANNWIVQNSWGTQWGESGNIRLYPQNTCGILNYPYQVY
  
Inhibitor
Name:
BDBM50153291
Synonyms:
(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold2,3,4,6-tetraacetate | AURANOFIN | CHEMBL1366 | Ridaura | SK&F-39162 | SK-39162
Type:
Small organic molecule
Emp. Form.:
C20H34AuO9PS
Mol. Mass.:
678.484
SMILES:
CC[P+](CC)(CC)[Au-]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O
Structure:
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