Reaction Details Report a problem with these data
Target
Putative cathepsin L 3
Ligand
BDBM50153290
Substrate
n/a
Meas. Tech.
ChEMBL_302746 (CHEMBL852353)
Ki
56000±n/a nM
Citation
 Chircorian, A; Barrios, AM Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I). Bioorg Med Chem Lett 14:5113-6 (2004) [PubMed]  Article 
Target
Name:
Putative cathepsin L 3
Synonyms:
CATL3_PARTE | Cathepsin L2
Type:
PROTEIN
Mol. Mass.:
35182.45
Organism:
Paramecium tetraurelia
Description:
ChEMBL_302746
Residue:
308
Sequence:
MKQFLTAAIVTLLMTAGYYHLQEDDTNDFERWALKNNKFYTESEKLYRMEIYNSNKRMIEEHNQREDVTYQMGENQFMTLSHEEFVDLYLQKSDSSVNIMGASLPEVQLEGLGAVDWRNYTTVKEQGQCASGWAFSVSNSLEAWYAIRGFQKINASTQQIVDCDYNNTGCSGGYNAYAMEYVLRVGLVSSTNYPYVAKNQTCKQSRNGTYFINGYSFVGGSQSNLQYYLNNYPISVGVEASNWQFYRSGLFSNCSSNGTNHYALAVGFDSANNWIVQNSWGTQWGESGNIRLYPQNTCGILNYPYQVY
  
Inhibitor
Name:
BDBM50153290
Synonyms:
CHEMBL182062 | Na[AuCl4] | gold chloride sodium | gold sodium chloride | hydrochloroauric acid, sodium salt | natrium tetrachloroauratum | sodium chloroaurate | sodium gold chloride | sodium gold(III) chloride | sodium tetrachloridoauratesodium tetrachloridoaurate(1-)sodium tetrachloridoaurate(III) | sodium tetrachloroaurate | sodium tetrachloroaurate(1-) | sodium tetrachloroaurate(III) | tetrachloroaurate(1-) sodium | tetrachloroauric(3+) acid, sodium salt
Type:
Small organic molecule
Emp. Form.:
AuCl3
Mol. Mass.:
303.326
SMILES:
Cl[Au](Cl)Cl
Structure:
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