Reaction Details Report a problem with these data
Target
Protein S100-B
Ligand
BDBM50154224
Substrate
n/a
Meas. Tech.
ChEMBL_302128 (CHEMBL841752)
Kd
4500±n/a nM
Citation
 Markowitz, J; Chen, I; Gitti, R; Baldisseri, DM; Pan, Y; Udan, R; Carrier, F; MacKerell, AD; Weber, DJ Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction. J Med Chem 47:5085-93 (2004) [PubMed]  Article 
Target
Name:
Protein S100-B
Synonyms:
S-100 protein beta chain | S100B | S100B_HUMAN
Type:
PROTEIN
Mol. Mass.:
10701.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_947124
Residue:
92
Sequence:
MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE
  
Inhibitor
Name:
BDBM50154224
Synonyms:
CHEMBL434915 | N-[4-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylsulfamoyl)-phenyl]-succinamic acid
Type:
Small organic molecule
Emp. Form.:
C21H22N4O6S
Mol. Mass.:
458.488
SMILES:
Cc1c(NS(=O)(=O)c2ccc(NC(=O)CCC(O)=O)cc2)c(=O)n(-c2ccccc2)n1C
Structure:
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