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Target
Protein S100-B
Ligand
BDBM50154225
Substrate
n/a
Meas. Tech.
ChEMBL_302128 (CHEMBL841752)
Kd
8100±n/a nM
Citation
 Markowitz, J; Chen, I; Gitti, R; Baldisseri, DM; Pan, Y; Udan, R; Carrier, F; MacKerell, AD; Weber, DJ Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction. J Med Chem 47:5085-93 (2004) [PubMed]  Article 
Target
Name:
Protein S100-B
Synonyms:
S-100 protein beta chain | S100B | S100B_HUMAN
Type:
PROTEIN
Mol. Mass.:
10701.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_947124
Residue:
92
Sequence:
MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE
  
Inhibitor
Name:
BDBM50154225
Synonyms:
2-(3-tert-Butylcarbamoyl-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid | CHEMBL365434
Type:
Small organic molecule
Emp. Form.:
C20H18N2O5
Mol. Mass.:
366.3673
SMILES:
CC(C)(C)NC(=O)c1cccc(c1)N1C(=O)c2ccc(cc2C1=O)C(O)=O
Structure:
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