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Target
D(3) dopamine receptor
Ligand
BDBM50155605
Substrate
n/a
Meas. Tech.
ChEMBL_303619 (CHEMBL828874)
Ki
84±n/a nM
Citation
 Wu, X; Chen, J; Ji, M; Varady, J; Levant, B; Wang, S Design, synthesis, and evaluation of hexahydrobenz[f]isoquinolines as a novel class of dopamine 3 receptor ligands. Bioorg Med Chem Lett 14:5813-6 (2004) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50155605
Synonyms:
3-Phenethyl-1,2,3,4,5,6-hexahydro-benzo[f]isoquinoline | CHEMBL186350 | CHEMBL554988
Type:
Small organic molecule
Emp. Form.:
C21H23N
Mol. Mass.:
289.414
SMILES:
C(Cc1ccccc1)N1CCC2=C(CCc3ccccc23)C1 |t:12|
Structure:
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