Reaction Details Report a problem with these data
Target
Fatty-acid amide hydrolase 1 [30-579]
Ligand
BDBM50157127
Substrate
n/a
Meas. Tech.
ChEMBL_303653 (CHEMBL829001)
Ki
54.0±n/a nM
Citation
 Du, W; Hardouin, C; Cheng, H; Hwang, I; Boger, DL Heterocyclic sulfoxide and sulfone inhibitors of fatty acid amide hydrolase. Bioorg Med Chem Lett 15:103-6 (2004) [PubMed]  Article 
Target
Name:
Fatty-acid amide hydrolase 1 [30-579]
Synonyms:
Anandamide amidohydrolase 1 | FAAH1_RAT | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty Acid Amide Hydrolic, FAAH | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Fatty-acid amide hydrolase 1 (FAAH) | Fatty-acid amide hydrolase 1 (aa 30-579) | Oleamide hydrolase 1
Type:
Single-pass membrane protein; homodimer
Mol. Mass.:
60474.00
Organism:
Rattus norvegicus (rat)
Description:
P97612 (aa 30-579)
Residue:
550
Sequence:
RWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFLQNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQHEIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQKQPS
  
Inhibitor
Name:
BDBM50157127
Synonyms:
(Z)-1-(5-(furan-2-yl)oxazol-2-yl)octadec-9-en-1-one | (Z)-1-(5-Furan-2-yl-oxazol-2-yl)-octadec-9-en-1-one | 1-(5-(furan-2-yl)oxazol-2-yl)octadec-9-en-1-one | CHEMBL174048
Type:
Small organic molecule
Emp. Form.:
C25H37NO3
Mol. Mass.:
399.5662
SMILES:
CCCCCCCC\C=C/CCCCCCCC(=O)c1ncc(o1)-c1ccco1
Structure:
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